The result on the variant on RNA or protein operate, depending on experimental evidence from submitters.
This value is calculated by NCBI based on details from submitters. Browse our regulations for calculating the critique status. The volume of submissions which contribute to this critique position is demonstrated in parentheses.
This date signifies the last time this VCV record was up to date. The update could possibly be as a consequence of an update to one of many bundled submitted records (SCVs), or as a result of an update that ClinVar designed on the variant for instance incorporating HGVS expressions or even a rs amount.
The global small allele frequency calculated from the a thousand Genomes Challenge. The minor allele at this site is indicated in parentheses and could be distinct through the allele represented by this VCV file.
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There isn't any citations for germline classification of the variant in ClinVar. If you are aware of of citations for this variation, please think about submitting that information to ClinVar.
The volume of variants in ClinVar which have been contained inside of this gene, using a link to perspective the list of variants.
These citations are determined by LitVar using the rs number, so they may include things like citations for multiple variant at this site. Make sure you overview the LitVar results diligently to your variant of fascination. History final up to date May well 19, 2024
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Stars symbolize the mixture evaluation standing, or the level of assessment supporting the combination germline classification for this VCV report.
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